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Editorial Reviews. From the Back Cover. Without a cytoskeleton, a neuron or glial cell would be a shapeless jelly mass unable to function in the milieu of the.
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The course focuses on how neuronal systems are designed to subserve specific motor, sensory, and cognitive operations. Neural mechanisms of animal behaviour; neuroethology; cellular neurophysiology, integrative networks within nervous systems; neural control of movement; processing of sensory information. In depth presentation of experimental results and hypotheses underlying our current understanding of how single neurons and ensembles of neurons encode sensory information, generate movement, and control cognitive functions such as emotion, learning, and memory, during voluntary behaviours.

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Comprehensive overview of programming in C, use of system calls and libraries, debugging and testing of code; use of developmental tools like make, version control systems. Mathematical tools binary numbers, induction, recurrence relations, asymptotic complexity, establishing correctness of programs , Data structures arrays, stacks, queues, linked lists, trees, binary trees, binary search trees, heaps, hash tables , Recursive and non-recursive algorithms searching and sorting, tree and graph traversal.

Abstract data types, inheritance. Where do thoughts come from? What is the nature of thought, and how does it arise in the mind and the brain? Cognition is the study of human information processing, and we will explore topics such as memory, attention, categorization, decision making, intelligence, philosophy of mind, and the mind-as computer metaphor.

The physiological bases of motivational states, with respect to feeding, drinking, sexual behavior, drug use, and aggression. Physiological bases of learning and memory.

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An introduction to pain research and theory, with emphasis on the interactions of psychological, cultural and physiological factors in pain perception. The role of these factors in clinical pain and its management by pharmacological and non-pharmacological means will be discussed. Not open to students who are taking or have taken PSYC Focuses on current techniques employed to study which genes influence behaviour, and how they do so. This course is not scheduled for the academic year.

There are no professors associated with this course for the academic year.

Cytoskeleton in Axon Growth

The role of hormones in organization of CNS function, as effectors of behaviour, in expression of behaviours and in mental illness. An introduction to laboratory techniques with a focus on methods used to investigate fundamental questions in modern cell and molecular biology. Techniques including gene cloning, DNA and protein isolation and manipulation are covered, along with functional analysis of genes and proteins, basic bioinformatics, and computer-based experimental design and data analysis. Not open to students who have taken or are taking BIOC For approval email anne-marie.

Specify your ID number as well as the term and two lab day preferences. Methods of neurobiological research, including extracellular and intracellular recordings, electrical stimulation, and the study of neuro-behavioural problems. Only open to students registered in the B. Not open to students who have taken or are taking NSCI The remainder of the credits should be taken from the following lists.

Major Neuroscience (65 credits)

A survey of current knowledge and approaches in the area of regulation of gene expression, post-transcriptional control of gene expression, and signal transduction. Functional and comparative approach to neuroanatomy, examining how species changes in brain organization contribute to evolutionary changes in behaviour. Modern spectroscopic techniques for structure determination.

The chemistry of alcohols, ethers, carbonyl compounds, and amines, with special attention to mechanistic aspects. First order ordinary differential equations including elementary numerical methods. Not open to students who have taken or are taking MATH Sample space, events, conditional probability, independence of events, Bayes' Theorem. Basic combinatorial probability, random variables, discrete and continuous univariate and multivariate distributions. Independence of random variables. Inequalities, weak law of large numbers, central limit theorem.

Intended for students in Science, Engineering and related disciplines, who have had differential and integral calculus. Sampling distributions, point and interval estimation, hypothesis testing, analysis of variance, contingency tables, nonparametric inference, regression, Bayesian inference. An intermediate-level immunology course covering the cellular and molecular basis of lymphocyte development and activation in immune responses in health and disease.

Neurology and Neurosurgery Faculty of Science. A survey of the functional organization of nerve cells, signalling in the nervous system, and principles of neural development. Topics include cell polarity, neurotransmitters, neurotrophins, receptors and second messengers, cell lineage, guidance of axon outgrowth, and nerve regeneration. Emphasis will be placed on analysis of neurons at the molecular level. Physiology of cardiovascular, respiratory, digestive, endocrine and renal systems.

For students in the Faculty of Science, and other students by permission of the instructor. Application of computational methods to the simulation of psychological phenomena. Comparison of natural and artificial intelligence. Symbolic and neural network techniques. Methods for evaluating simulations. Properties of nerve cells that are responsible for learning and memory. Recent advances in the understanding of neurophysiological, biochemical and structural processes relevant to neural plasticity.

Emphasis on a few selected model systems involving both vertebrate and invertebrate animals. Neural mechanisms underlying behaviour in vertebrate and invertebrate organisms. Discussions of all aspects of nervous system development including pattern formation, cell lineage, pathfinding and targeting by growing axons, and neural regeneration. The basis for these discussions will be recent research papers and other assigned readings. This course will focus on recent research employing genetic-based methods to examine the functional and structural properties of the nervous system.

Neurobiology 3. Lec. - Axon Growth and Guidence [4/7]

The focus will be on approaches for studying neural circuits and behavior in a range of model organisms. Topics will include recent technological advances, such as optogenetics for modifying and controlling neuronal activity, and animal models of neurological diseases. Students will critically analyze the application of these methods to current research through in-class discussion of primary literature, student presentations, and written assignments.

BIOL or permission of the instructors. Discussion of fundamental molecular mechanisms underlying the general features of cellular neurobiology. An advanced course based on lectures and on a critical review of primary research papers. Biomedical Engineering Faculty of Engineering. An introduction to the theoretical framework, experimental techniques and analysis procedures available for the quantitative analysis of physiological systems and signals. Lectures plus laboratory work using the Biomedical Engineering computer system.

Computational models of visual perception and audition. Vision problems include stereopsis, motion, focus, perspective, color. Audition problems include source localization and recognition. Emphasis on physics of image formation, sensory signal processing, neural pathways and computation, psychophysical methods. Not open to students who have taken COMP The formulation and treatment of realistic mathematical models describing biological phenomena through qualitative and quantitative mathematical techniques e.

Concrete and detailed examples will be drawn from molecular and cellular biology and mammalian physiology. An advanced course serving as a logical extension of MIMM The course will integrate molecular, cellular and biochemical events involved in the ontogeny of the lymphoid system and its activation in the immune response. The course will provide the student with an up-to-date understanding of a rapidly moving field.


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This course concentrates on the non-specific aspects of the immune response, an area which is not adequately covered by the other immunology courses presented at the university. Interactions between guest researchers from McGill and other universities and students will be furthered. Neurology and Neurosurgery Faculty of Medicine.

The course deals with neuroreceptor and oncologic imaging and imaging of cerebral bloodflow and metabolism. The role of radiochemistry and physics will be demonstrated in the context of clinical and research applications. Understanding how radiochemistry and physics intermingle with the medical aspects of radiotracer development will result in a deeper insight into the complex pathways of tracer design and the methods necessary to properly interpret the data obtained.

Not open to students who have taken NEUR Topics in pharmacology with an emphasis on molecular mechanisms of drug-action and cellular targets in the nervous system. PHAR or with permission of instructor. Open to U3 students in the minor, major or honours program in Pharmacology, or with permission of instructor. An introduction to quantitative analysis of physiological data, both to the mode of thinking and to a set of tools that allows accurate predictions of biological systems. Examples will range from oscillating genetic networks to understanding higher brain function.

Modelling and data analysis through examples and exercises will be emphasized. Topics of current interest in neurophysiology including the development of neurons and synapses, physiology of ionic channels, presynaptic and postsynaptic events in synaptic transmission and neuronal interactions in CNS function. This course deals with cellular interactions, regulation and effector mechanisms of the normal immune response in relation to diseases and pathogenic processes.

It is taught at an advanced level. MIMM , or permission of the instructor. A discussion of the principal theories and interesting new developments in the study of ion channels. Based on a textbook, computer exercises and critical reading and presentation of research papers. Properties of voltage-and ligand-gated channels, single channel analysis, structure and function of ion channels. An introduction to the field of chronobiology. The aim is to provide basic instruction on different types of biological rhythms, with particular focus on circadian rhythms.

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If you are a seller for this product, would you like to suggest updates through seller support? This monograph begins with a general description of the cytoskeleton in axonal development and pathology and then moves to more detailed descriptions of particular components, including microtubules and associated proteins, neurofilaments and interacting proteins, actin and its binding proteins, and glial fibrillary acidic protein.

The later chapters focus on the functional significance of the neuronal cytoskeleton in axonal transport and its regulation in health and disease states.


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The Cytoskeleton of the Nervous System will encourage further development of unifying principles and stimulate new conceptual and technical approaches toward a better understanding of cytoskeleton functions in health and disease. Read more Read less. From the Back Cover Without a cytoskeleton, a neuron or glial cell would be a shapeless jelly mass unable to function in the milieu of the brain.

Advances in Neurobiology Book 3 Hardcover: Springer; edition February 14, Language: Be the first to review this item Amazon Best Sellers Rank: Try the Kindle edition and experience these great reading features: Share your thoughts with other customers. Write a customer review. Kline Institute for Psychiatric Research. Would you like to tell us about a lower price? If you are a seller for this product, would you like to suggest updates through seller support?

This monograph begins with a general description of the cytoskeleton in axonal development and pathology and then moves to more detailed descriptions of particular components, including microtubules and associated proteins, neurofilaments and interacting proteins, actin and its binding proteins, and glial fibrillary acidic protein. The later chapters focus on the functional significance of the neuronal cytoskeleton in axonal transport and its regulation in health and disease states. The Cytoskeleton of the Nervous System will encourage further development of unifying principles and stimulate new conceptual and technical approaches toward a better understanding of cytoskeleton functions in health and disease.

Read more Read less. From the Back Cover Without a cytoskeleton, a neuron or glial cell would be a shapeless jelly mass unable to function in the milieu of the brain. Advances in Neurobiology Book 3 Hardcover: Springer; edition February 14, Language: Be the first to review this item Amazon Best Sellers Rank: Try the Kindle edition and experience these great reading features: